Not being able to stand the cold. Constipation. Memory problems or having trouble thinking clearly. Heavy or irregular menstrual periods. Symptoms occur slowly over time. At first you might not notice them, or you might mistake them for normal aging.
See Lipoprotein profile in subclinical hypothyroidism: response to levothyroxine replacement, a randomized placebo-controlled study. J Clin Endocrinol Metab. 2002 Apr;87(4 1533-8. Similarly, female patients with a slight TSH elevation with no other symptoms, often referred to as subclinical hypothyroidism, appear to have a modest excess of cardiac risk factors, including increased blood pressure and cholesterol.
Weight gain Muscle aches and cramps Hair loss. Sleep disorders Dry skin Feeling cold Menstrual irregularities. Fluid retention or puffiness In mild forms of hypothyroidism, patients may feel completely well, and have no symptoms.
As thyroid hormone has a long half life, it takes 3-4 weeks for a new steady state level of thyroid hormone to equilibrate in the blood. Hence retesting too early after initiation of thyroxine may give inaccurate results.
See Thyroid disease and the heart. Indeed, having too much T3 can be an independent risk factor for development of heart disease, as seen in Excess triiodothyronine as a risk factor of coronary events Arch Intern Med 2000 10;160(13 1993-9.
Medicines. Medicines such as amiodarone, lithium, interferon alpha, and interleukin-2 can prevent the thyroid gland from being able to make hormone normally. These drugs are most likely to trigger hypothyroidism in patients who have a genetic tendency to autoimmune thyroid disease.
The thyroid makes two kinds of thyroid hormone: thyroxine, called T4, and T3. The thyroids output consists primarily of T4 (see Figure 1 below). Most of the T3 the body needs is made outside the thyroid, in organs and tissues that use T3, such as the liver, kidneys and brain.
If your doctor thinks you have hypothyroidism, a simple blood test can show if your thyroid hormone level is too low.
J Postgrad Med. 2004 Jan-Mar;50(1 7-10. Moreover, there is some evidence that "normal" TSH levels may vary with age, as older individuals may have somewhat higher levels of TSH, yet still have no evidence of thyroid dysfunction, as outlined in Age-Specific Distribution of Serum TSH and Antithyroid Antibodies in the United States Population; Implications for.
With Hashimotos thyroiditis the immune system mistakenly produces antibodies against the thyroid and attacks it as if it did not belong there. Antibodies against the thyroid are anti-thyroglobulin antibodies (TgAb) and anti-microsomal/thyroid peroxidase antibodies (TPOA b).