Australian prescription products guide online. Available from: URL: p." (2006 United States National Library of Medicine "Toxnet. Toxicology Data Network. Available from: URL: h.gov/cgi-bin/sis/htmlgen? LACT." (cited 2013 - "Product Information. Synthroid (levothyroxine)." Abbott Pharmaceutical, Abbott Park, IL.
-If this drug is required by the mother, it is not a reason to discontinue breastfeeding. -This drug is recommended treatment for postpartum thyroiditis and tapering of the dose should be avoided when a woman is breastfeeding.
Although the effects of this modest level of hypothyroidism are not known, we think it prudent to monitor thyroid function throughout gestation and after delivery and to adjust the thyroxine dose to maintain a normal serum thyrotropin level.
The extra care you receive will help you to have a healthy and successful pregnancy. Last reviewed: June 2014 References ACB, BTA, BTF. 2006. UK guidelines for the use of thyroid function tests.
Because of high thyrotropin levels, the thyroxine dose was increased in 9 of the 12 patients. Among the three patients who did not require an increased thyroxine dose were two with low serum thyrotropin levels before pregnancy, suggesting excessive replacement at that time.
-The dosage requirement of this drug may be increased in the postpartum period compared to prepregnancy requirements patients with Hashimoto's thyroiditis. See references References for pregnancy information Pharmaceutical Society of Australia "APPG uide online.
Excreted into human milk: Yes (minimumally) Comments: -This drug is a normal component of human milk. -Limited data on use of this drug during breastfeeding indicate no adverse effects in infants.
-Thyroid hormones cross the placental barrier to some extent as evidenced by levels in cord blood of athyreotic fetuses being approximately one-third maternal levels. Transfer of thyroid hormone from the mother to the fetus, however, may.
Correct thyroxine levels are important for your babys brain development so your doctor will monitor your thyroid function more frequently during pregnancy. In most instances, your GP will be able to monitor your thyroid levels, however if they do not stabilise you may be referred to a specialist.
The mean postpartum thyroxine dose was decreased to 0.117 /- 0.011 mg per day (P less than 0.01 as compared with the dose during pregnancy). CONCLUSIONS : Our results indicate that the need for thyroxine increases in many women with primary hypothyroidism when they are pregnant, as reflected by an increase in serum thyrotropin concentrations.
Therefore, the possibility of fetal harm appears remote. This drug should not be discontinued during pregnancy and hypothyroidism diagnosed during pregnancy should be promptly treated. -Hypothyroidism during pregnancy is associated with a higher rate of complications, including spontaneous abortion, pre-eclampsia, stillbirth and premature delivery.
London: RCOG Press. pdf file, accessed May 2012 NHS NSP. 2010. Screening tests for your baby. NHS National Screening Programme. pdf file, accessed May 2012. PRODIGY. 2011. Hypothyroidism management: preconception or pregnant.
Australian prescription products guide online. Available from: URL: p." (2006 "Product Information. Synthroid (levothyroxine)." Abbott Pharmaceutical, Abbott Park, IL. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0. References for breastfeeding information Moller B, Bjorkhem I, Falk O, Lantto O, Lafsson A "Identification of thyroxine in human breast milk by gas chromatography-mass spectrometry." J.
Maternal hypothyroidism may have an adverse effect on fetal and childhood growth and development. -During pregnancy, serum T4 levels may decrease and serum TSH levels increase to values outside the normal range.
You should be tested at regular intervals to ensure your thyroxine levels are within the normal range. If you are pregnant, it is likely that your thyroxine requirements will increase to help your body cope with pregnancy and a growing baby.
-Since postpartum TSH levels are similar to preconception values, the dosage should return to the pre-pregnancy dose immediately after delivery. A serum TSH level should be obtained 6 to 8 weeks postpartum.
US: US FDA pregnancy category A: Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
About one in 20 will be found to have abnormal thyroxine levels. If your thyroxine levels are too low, your doctor will prescribe a thyroxine replacement, which can help to regulate your periods, promote ovulation and improve your fertility.
BACKGROUND AND METHODS : Women with hypothyroidism have been thought not to require an increase in thyroxine replacement during pregnancy. To evaluate the effects of pregnancy on thyroxine requirements, we retrospectively reviewed the thyroid function of 12 women receiving treatment for primary hypothyroidism before, during, and after pregnancy.