For the purpose of illustration, consider one mechanism by which thyroid hormones increase the strength of contraction of the heart. Cardiac contractility depends, in part, on the relative ratio of different types of myosin proteins in cardiac muscle.
A few examples of specific metabolic effects of thyroid hormones include: Lipid metabolism : Increased thyroid hormone levels stimulate fat mobilization, leading to increased concentrations of fatty acids in plasma. They also enhance oxidation of fatty acids in many tissues.
Growth: Thyroid hormones are clearly necessary for normal growth in children and young animals, as evidenced by the growth-retardation observed in thyroid deficiency. Not surprisingly, the growth-promoting effect of thyroid hormones is intimately intertwined with that of growth hormone, a clear indiction that complex physiologic processes like growth depend upon multiple endocrine controls.
Jul 26, 2012. The physiologic effects of triiodothyronine (T3) on metabolic rate are well- documented; however, the effects of thyroxine (T4) are less clear.
Additionally, many of the effects of thyroid hormone have been delineated by study of deficiency and excess states, as discussed briefly below. Metabolism : Thyroid hormones stimulate diverse metabolic activities most tissues, leading to an increase in basal metabolic rate.
Aug 16, 2013. A person s basal metabolic rate refers. Thyroxine s Effect on Metabolism. gland and what controls the body s basal metabolic rate (BMR).
Most cases of hypothyroidism are readily treated by oral administration of synthetic thyroid hormone. In times past, consumption of dessicated animal thyroid gland was used for the same purpose. Hyperthyroidism results from secretion of thyroid hormones.
They also promote vasodilation, which leads to enhanced blood flow to many organs. Central nervous system : Both decreased and increased concentrations of thyroid hormones lead to alterations in mental state.
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Thyroid Hormone Receptors. Physiologic Effects of Thyroid Hormones It is likely that all cells in the body are targets for thyroid hormones. While not strictly necessary for life, thyroid hormones have profound effects on many "big time" physiologic processes, such as development, growth and metabolism, and deficiency in thyroid hormones is not compatible with normal.
Too much thyroxine causes a BMR that is too high. This leads to Graves' disease, a condition pertaining to an overactive thyroid. Too much thyroid hormone in the bloodstream can create extremes in body weight due to differences in basal metabolic rate.
Jul 24, 2010. Metabolism: Thyroid hormones stimulate diverse metabolic activities most tissues, leading to an increase in basal metabolic rate.
Last Updated: Aug 16, 2013 By Susan Kaye. Susan Kaye. Susan Kaye writes about alternative health care, the medicinal value of foods and natural remedies for healing body, mind and spirit.