There is no obvious explanation for these observations, and it may or may not be a reproducible effect. E. The BTA keeps an open mind about whether using an appropriate formulation of T4/T3 combination tablet would, in the future, provide health and quality of life benefits in the treatment of hypothyroidism for a subgroup of.
C. Since this initial study, there have been a further seven rigorously conducted (randomised, double-blind, placebo-controlled) studies, encompassing more than 900 hypothyroid patients 5,6. None of the subsequent studies showed a beneficial effect of combined T4/T3 therapy on measures of wellbeing, health and mental functioning.
UK. Mr. G. Matthews, the Pharmaceutical Assessor of the Medicines and Health Care Products. Regulatory Agency, in a letter sent to BTA dated, has clarified that The regulations on medicine allow doctors to prescribe an unlicensed medicine for a patient to meet such a special clinical need, on their own direct personal responsibility.
Historically, extracts of animal thyroid glands were the only way to treat thyroid underactivity, but since the 1950s pure synthetic thyroid hormones have been available in tablet form (thyroxine sodium T4 and liothyronine T3).
In other words, Armour thyroid extract contains excessive amounts of T3 relative to T4 when used to replace thyroid hormone in man. Moreover, as pig thyroid contains other substances apart from T4 and T3, Armour Thyroid is not a pure preparation of thyroid hormones.
What s the big deal about natural desiccated thyroid (NDT)?. Chapter One of the revised STTM book details what each of these hormones are. A lot of patients who ve tried T4-only, or even the two synthetics (T4 and T3) or even straight T3,.
A patient asked Australian Custom Pharmaceuticals, Australias largest compounding-only pharmacy, about their ingredients. It was stated that the only ingredients put in the capsules are the active ingredient (thyroid extract) and microcrystalline cellulose as the filler.
Levothyroxine is the main thyroid hormone produced by the thyroid gland and the synthetic form is the most common form of thyroid hormone replacement therapy. Prior to the availability of the pure levothyroxine, desiccated animal thyroid extract was the only treatment for hypothyroidism.
Another thyroid patient, Daniella, was told by the makers of Thiroyd that is free of aluminum, which is good news if you are avoiding excesses of aluminum for any reason. As of 5-2013, here are potential fillers as sent to me by a patient in Guam: Lactose, Tapioca Starch, Sodium Starch Glycolate, PVP K-30, PVP K-90.
The participants were "blinded" during both phases they did not know the type of pill they received. After each treatment period patients were weighed, had blood tests, underwent psychometric testing and were asked which therapy they preferred.
Three of the seven studies show harmful or undesirable effects of the T4/T3 combination. D. In three of the subsequent studies of combination treatment, the patients were asked which treatment they preferred, and in two of these 3 studies more patients preferred the combination T4/T3 therapy.
The researchers report that 49 of the patients preferred desiccated thyroid extract, 19 preferred levothyroxine and 23 had no preference. Desiccated thyroid extract use was also associated with more weight loss.
C. There is no evidence to favour the prescription of Armour Thyroid in the treatment of hypothyroidism over the prescription of thyroxine sodium, as supplied in the United Kingdom. There has never been a direct comparison of these two treatments.
Today, some individuals prefer dessicated thyroid extract as a more "natural" thyroid hormone. In addition, some patients who continue to have symptoms of hypothyroidism when taking levothyroxine report improvement in these symptoms when switched to desiccated thyroid extract.