If better control can be achieved with levothyroxine then the patient is better served by an endocrinologist prescribing thyroid drugs. However, when there are still unresolved h.
C. There is no evidence to favour the prescription of Armour Thyroid in the treatment of hypothyroidism over the prescription of thyroxine sodium, as supplied in the United Kingdom. There has never been a direct comparison of these two treatments.
Batch Variations in Desiccated Thyroid Preparations. Although the USP (United States Pharmacopeia) specifies the standard concentration for T4 and T3 in thyroid gland preparations, the reality is that there is a wide variation in the concentrations of the thyroid hormones in desiccated thyroid extract available in the market.
Since desiccated thyroid is a natural combination of these two thyroid hormones, it follows that it is more effective for all cases of hypothyroidism than thyroid drugs Besides T3 and T4, desiccated thyroid contains other active constituents that can contribute to the effectiveness of the preparation.
Endocrinologists believe desiccated thyroid is an antiquated remedy for hypothyroidism. However, there are other reasons for the shift to new thyroid drugs. Discussed below are some of the big reasons driving this change.
UK. Mr. G. Matthews, the Pharmaceutical Assessor of the Medicines and Health Care Products. Regulatory Agency, in a letter sent to BTA dated, has clarified that The regulations on medicine allow doctors to prescribe an unlicensed medicine for a patient to meet such a special clinical need, on their own direct personal responsibility.
In some ways, let's admit it - Dr. Repas is more open-minded than some endocrinologists. There are some who simply will not have as patients anyone on a T3 drug or desiccated thyroid.
Over at the Endocrine Today blog, endocrinologist and osteopath Thomas Repas, DO, FACP, FACE, CDE, has done a three-part article on "Desiccated thyroid in the management of hypothyroidism from his perspective as an endocrinologist.
But if a patient is already on it and doing well, he won't "argue with success" and will continue to prescribe the desiccated thyroid for him or her? Where is the "science" in that approach?
Levothyroxine is the most common form of thyroid hormone replacement therapy. Prior to the availability of the pure levothyroxine, desiccated animal thyroid extract.
For every 65 mg of desiccated thyroid, the USP specifies that 38 micrograms of T3 and 9 micrograms of T4 be present. However, a survey of different desiccated thyroid extract brands shows that T3 concentrations may vary from 8 micrograms to 59 micrograms while T4 is usually found in the 8 18 microgram range.
There is no obvious explanation for these observations, and it may or may not be a reproducible effect. E. The BTA keeps an open mind about whether using an appropriate formulation of T4/T3 combination tablet would, in the future, provide health and quality of life benefits in the treatment of hypothyroidism for a subgroup of.
Since there are other sources of iodine in desiccated thyroid besides T3 and T4, there will always be variations in the contents of desiccated thyroid pills. In a way, the standardization of desiccated thyroid by iodine content represents the old method of treating hypothyroidism by increasing iodine levels.
Neither is there a preparation that produces a sustained release of thyroid hormones in a pattern similar to that from the human thyroid gland. B. Having been disregarded as a therapeutic approach to the treatment of hypothyroidism since the 1970s, interest in combination thyroxine/tri-iodothyronine (T4/T3) therapy was re-ignited by a study of 31 patients published.
Recently, there is a new movement towards treating hypothyroidism with desiccated thyroid. As more people turn to alternative medicine, an increasing number of patients, alternative medicine practitioners and even some doctors are turning to desiccated thyroid especially after considering its long track record of safety and efficacy.
Historically, extracts of animal thyroid glands were the only way to treat thyroid underactivity, but since the 1950s pure synthetic thyroid hormones have been available in tablet form (thyroxine sodium T4 and liothyronine T3).